WebNov 20, 2024 · CheckMate-032 investigator Jonathan E. Rosenberg, MD, discusses extended follow-up findings from the trial, as well as the future of immunotherapy in … WebJan 27, 2024 · Urothelial cancer of the bladder, renal pelvis, ureter, and other urinary organs is the fifth most common cancer in the United States, and systemic platinum-based chemotherapy remains the standard of care for first-line treatment of advanced/metastatic urothelial carcinoma (UC). Until recently, there were very limited options for patients …
Rosenberg Discusses Takeaways From CheckMate-032 Data in Urothelial …
WebDec 2, 2024 · CheckMate-032 Study: promising efficacy with nivolumab-based immunotherapy in pretreated esophagogastric cancer J Thorac Dis . 2024 Mar;11(Suppl … WebOct 20, 2024 · CheckMate -032 is a multi-center, open-label Phase 1/2 trial, evaluating the safety and efficacy of Opdivo as a single agent or in combination with Yervoy in 274 patients with previously treated locally advanced or metastatic urothelial carcinoma (mUC), RECIST v1.1 measurable disease, and ECOG performance status ≤1. hasaminoa-to
Nivolumab Alone and With Ipilimumab in Previously Treated …
WebOn the basis of CheckMate 274 results, nivolumab improved clinical outcomes when administered as adjuvant therapy to patients with urothelial carcinoma at high risk for … WebMay 17, 2024 · CheckMate 032 is an open-label, multicohort study that includes patients with unresectable locally advanced or metastatic urothelial carcinoma (mUC) treated with nivolumab 3 mg/kg monotherapy every 2 weeks (NIVO3), nivolumab 3 mg/kg plus ipilimumab 1 mg/kg every 3 weeks for four doses followed by nivolumab monotherapy 3 … WebMar 18, 2024 · Background Immune checkpoint inhibitors (ICI) are an integral part of bladder cancer therapy, however, the relevance of ICI treatment for mixed and pure squamous cell carcinoma of the bladder remains poorly studied. Therefore, we analysed the expression of programmed death-ligand 1 (PD-L1) in urothelial carcinomas with squamous … hasami porcelain tall teapot