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WebAug 3, 2013 · Drug incompatibility can provoke physical and/or chemical reactions. Physical incompatibilities result in visible (precipitate, colour change, gas production) and invisible (sub-visible particles, variations in pH) reactions, and even in the absence of precipitate could result in a significant reduction in the amount of drug delivered to the patient. WebThe addition of paracetamol to Zinnat ® produced an appearance of new peaks at 97.0˚C and 149.8˚C as well as broadening and reducing the endothermic peak present at 181.8˚C to 176.1˚C, which indicate an interaction between paracetamol and Zinnat ®.. DSC curves for the binary mixtures (1:1 w/w) consist of paracetamol and pure antibiotics (amoxicillin, … cure for constant hiccups
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